Platelet-rich plasma (PRP) therapy has gained attention for its potential to rejuvenate ageing skin, speed up healing, and even stimulate hair growth. Sometimes nicknamed the ‘vampire’ treatment it’s earned this grisly moniker because the treatment is made from your own blood.
In this article, we’ll explore what PRP is, how it works for hair loss, what the research says, and how it compares with Minoxidil.
What is PRP?
To create the PRP, a small blood sample is drawn and spun in a centrifuge, separating the platelets from the other blood components.
Platelets help stop bleeding by forming blood clots when we injure ourselves, but they also release proteins called growth factors, which help to heal wounds and repair damaged tissue. For hair restoration, the PRP is injected directly into the patient’s scalp, where it is thought to stimulate the hair follicle.
Researchers believe PRP helps to extend the anagen (growth) phase of the hair cycle and protect against premature catagen transition. If you want to know more about the different stages of the hair growth cycle, you can read about it here.
Treatment usually involves three sessions, about a month apart, with maintenance sessions every 3-6 months to keep up results.
How well does PRP work as a hair loss treatment?
The studies so far on PRP as a hair growth treatment are very promising.
Of the research that has been conducted so far, most highlight that PRP can significantly improve both hair density and diameter when compared to a placebo group. A 2021 study on mice found hair count, diameter, and density increased in a group who received 3 PRP sessions three months apart. There have been some studies which found conflicting results, like this 2020 study which found no statistical difference in hair density or thickness between participants treated with PRP and placebo.
How does it compare to Minoxidil?
Minoxidil, available as a topical solution or oral capsule, is one of the most widely used and well-studied hair loss treatments. When comparing PRP with Minoxidil, findings were mixed.
One study found both PRP and Minoxidil to significantly improve hair count and density in participants, with no statistical difference between the two groups. A different study found PRP to be more effective than 5% Minoxidil.
The conflicting results are seemingly attributed to the lack of standardisation of how PRP treatments should be administered. Factors such as how many times the blood is spun, how concentrated the sample is, and how often injections are given can all influence results. For example, some studies spun the blood sample in the centrifuge more than once, which meant the PRP was more concentrated. Until PRP methods are standardised, it’s difficult to say with certainty whether it consistently outperforms Minoxidil.
Are there any side effects?
Side effects from PRP treatments are usually mild and temporary. They may include pain, headaches, redness/swelling and temporary hair shedding. PRP may not be suitable for patients with certain health conditions such as anaemia, clotting disorders, or cancer. It’s important that PRP is carried out by a qualified medical professional to ensure both safety and effectiveness.
The bottom line
Minoxidil: Clinically proven, MHRA-approved treatment
- PRP: A newer, promising option that may deliver results similar to Minoxidil, but evidence is still evolving.
If you’re considering PRP, think of it as a potentially powerful addition to the hair loss toolkit, but not yet a guaranteed replacement for proven treatments like Minoxidil. Always consult a medical professional to determine the best approach for your specific needs.
All of our blog articles are reviewed by our Medical Director before publication.
